On August 28 2003, Madonna performed Hollywood with Britney Spears and Christina Aguilera as the opening number for the 20th annual MTV Video Music Awards at Radio City Music Hall, New York, NY and upstaged everyone at the ceremony when she shares a passionate open-mouth kiss with them. Missy Elliott also joined the ladies on stage – post-kiss.

Madonna commented on the uproar surrounding the infamous kiss during an appearance on Oprah several weeks later.  “I don’t know why people are making such a big deal about it,” she said. “Hasn’t anyone seen two girls kiss before? It was a friendly kiss – it really was. If Britney looks as though she is kissing me in an aggressive way it was a surprise to me.” She added, “I’m a showgirl. After 20 years in the business, we learn to roll with the punches. If someone’s coming at you with lips slightly parted, you kiss them.”