On July 21 1987, the Who’s That Girl: Original Motion Picture Soundtrack album was released.

Who’s That Girl was released as the lead single from the soundtrack, it became Madonna’s sixth single to top the Billboard Hot 100 chart, making her the first artist to accumulate six number-one singles in the 1980s, and the first female performer to earn that many number-ones as a solo act.

The album’s second single, Causing a Commotion, was released on August 25, 1987. In the United States, the single quickly climbed up the chart, ultimately peaking at number two in the week of October 24, 1987, the same week Michael Jackson’s Bad advanced to the pole position. It remained in second position for three weeks, before descending from the chart.

The third song released from the album was the European single The Look of Love. In the United Kingdom, The Look of Love was released on December 12, 1987, and entered the UK Singles Chart at position 15.  The next week, it reached a peak of nine on the chart, her first single to miss the top five since Lucky Star in 1984.

Regarding her contributions to the soundtrack, Madonna said:

“I had some very specific ideas in mind, music that would stand on its own as well as support and enhance what was happening on-screen and the only way to make that a reality was to have a hand in writing the tunes myself… The songs aren’t necessarily about Nikki or written to be sung by someone like her, but there’s a spirit to this music that captures both what the film and the characters are about, I think.”

The only Madonna song not to be released as a single or performed live from the soundtrack was Can’t Stop. Madonna had been performing her three other songs from the soundtrack during the Who’s That Girl World Tour for over a month prior to the album’s release.