On May 19 1995, the music video for Human Nature premiered on MTV.

Madonna had initially planned to have friend and collaborator Alek Keshishian direct the video for Human Nature. Keshishian had even been named as the director in ICON Magazine, but for unknown reasons this shoot was cancelled during pre-production. Madonna later called in another recurring collaborator – Jean-Baptiste Mondino – to direct the clip instead.

The video marked Madonna’s first collaboration with Jamie King, who can be spotted as a dancer in the video.